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Independent, randomised, placebo controlled.

About the positive effect of Sanience D3 Spray form on D3 vitamin levels in the blood.

EVIDENCE
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RESULTS

Average vitamin D levels (ng/mL) of the participants of the Sanience D3 group study at the beginning of the study and after 30 days of using Sanience D3.

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CONFIRMED
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The participants of the study highlighted the advantages of Sanience D3.

PROVEN EFFECTIVENESS

Absorption of vitamin D3 in the body. How efficiently is vitamin D3 absorbed in the body 30 minutes after using Sanience D3 in spray form based on a microemulsion as proportionally compared to other vitamin D3 sprays based on oil and water available on the market.

97%

Confirm that optimal levels of vitamin D guarantee a string immune system

96%

Attest that vitamin D needs to be supplemented daily

96%

Acknowledge that vitamin D plays a vital role in overall health

95%

Confirm that vitamin D needs to be supplemented daily throughout the year

The research confirmed the scientific assumption that the Sanience D3 dietary supplement provides highly absorbable vitamin D, which promotes adequate levels of vitamin D in the blood thus supporting autoimmune disease prevention[1][2][3][4], improving psycho-emotional health [5][6], reducing risk of oncological disease[7], promoting strong bones and calcium absorption.

The research confirmed the effectiveness of a therapeutic dose (8000 IU/day) of Sanience D3 in preventing insufficient or deficient levels (10-29,9 ng/mL) of vitamin D for inhabitants of Latvia with short-term use (30 days).

The research observed several types of oral spray vitamin D products and analysed their ability in the short term to effectively raise overall levels of vitamin D in people with insufficient or deficient levels of vitamin D. The study involved 111 participants divided into three groups, one of which received a placebo.

The research was designed by SIA InCell in collaboration with SIA Centrālā laboratorija and SIA NCL following the 05.02.2020 positive opinion from the Scientific Research Ethics Committee of the Institute of Cardiology and Regenerative Medicine of the University of Latvia.

Further information about the research is available from SIA pharm&med.

[1] Twig G, Shina A, Amital H, Shoenfeld Y. Pathogenesis of infertility and recurrent pregnancy loss in thyroid autoimmunity. J Autoimmun. 2012;38:J275– J281;
[2] Cantorna MT, Mahon BD. D-hormone and the immune system. J Rheumatol Suppl. 2005;76:11 20.;
[3] Deluca HF, Cantorna MT. Vitamin D: its role and uses in immunology. FASEB J. 2001;15:2579–2585;
[4] Chen-Yen Yang, Patrick S. C. Leung, Iannis E. Adamopoulos, and M. Eric Gershwin. The Implication of Vitamin D and Autoimmunity: a Comprehensive Review.;
[5] Reinhold Vieth, Samantha Kimball,1Amanda Hu,and Paul G Walfish Randomized comparison of the effects of the vitamin D3 adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patients;
[6] Witte J. G. Hoogendijk, MD, PhD; Paul Lips, MD, PhD; Miranda G. Dik, PhD Depression Is Associated With Decreased 25-Hydroxyvitamin D and Increased Parathyroid Hormone Levels in Older Adults;
[7] Giovannucci E, Liu Y, Rimm EB, et al. Prospective study of predictors of vitamin D status and cancer incidence and mortality in men. J Natl Cancer Inst. 2006;98:451–459.;

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